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Unité Matériaux et Transformations
CNRS UMR 8207 - Université de Lille

DESCAMPS Marc
Marc DESCAMPS
Professeur
Bâtiment P5 - 221
Unité Matériaux et Transformations
Cité scientifique, Bât. P5
Université de Lille
59655 Villeneuve d'Ascq
France
Tel: +33 (0)3 20 43 49 79
Fax: +33 (0)3 20 43 40 84
Courriel: marc.descamps@univ-lille.fr

Recherche

Cristaux moléculaires désordonnés : Cristaux vitreux, cinétiques de transformations de phase, mobilité moléculaire à l’état cristallin. Verres et transition vitreuse de composés moléculaires. Physique des Solides Pharmaceutiques. Matériaux moléculaires forcés (transformations induites par broyage)

Edition

Thèses soutenues

Derniers dépôts dans dans LillOA (Lille Open Archive)

Publications

  1. P.F.M. Oliveira, J. willart, J. Siepmann, F. Siepmann, M. Descamps, Using Milling To Explore Physical States: The Amorphous and Polymorphic Forms of Dexamethasone, Crystal Growth & Design 18, 1748-1757 (2018), [doi: 10.1021/acs.cgd.7b01664, LillOA]
  2. M. Descamps, J. willart, Scaling laws and size effects for amorphous crystallization kinetics: Constraints imposed by nucleation and growth specificities, International journal of pharmaceutics 542, 186-195 (2018), [doi: 10.1016/j.ijpharm.2018.03.001, LillOA]
  3. A. Mahieu, J. willart, M. Guerain, P. Derollez, F. Danede, M. Descamps, Structure determination of phase II of the antifungal drug griseofulvin by powder X-ray diffraction, Acta Crystallographica Section C Structural Chemistry 74, 321-324 (2018), [doi: 10.1107/S2053229618001845, LillOA]
  4. E. Elisei, J. willart, F. Danede, J. Siepmann, F. Siepmann, M. Descamps, Crystalline Polymorphism Emerging From a Milling-Induced Amorphous Form: The Case of Chlorhexidine Dihydrochloride, Journal of Pharmaceutical Sciences 107, 121-126 (2018), [doi: 10.1016/j.xphs.2017.07.003, LillOA]
  5. P. Martinetto, P. Bordet, M. Descamps, E. Dudognon, W. Pagnoux, J. willart, Structural Transformations of d -Mannitol Induced by in Situ Milling Using Real Time Powder Synchrotron Radiation Diffraction, Crystal Growth & Design 17, 6111-6122 (2017), [doi: 10.1021/acs.cgd.7b01283, LillOA]
  6. J. willart, E. Dudognon, A. Mahieu, M.D. Eddleston, W. Jones, M. Descamps, The role of cracks in the crystal nucleation process of amorphous griseofulvin, The European Physical Journal Special Topics 226, 837-847 (2017), [doi: 10.1140/epjst/e2016-60358-y, LillOA]
  7. A. Benazzouz, E. Dudognon, N. T. Correia, V. Molinier, J.-M. Aubry, M. Descamps, Interactions underpinning the plasticization of a polymer matrix: a dynamic and structural analysis of DMP-plasticized cellulose acetate, Cellulose 24, 487-503 (2017), [doi: 10.1007/s10570-016-1148-y, LillOA]
  8. P. Bordet, A. Bytchkov, M. Descamps, E. Dudognon, E. Elkaïm, P. Martinetto, W. Pagnoux, A. Poulain, J. willart, Solid State Amorphization of β-Trehalose: A Structural Investigation Using Synchrotron Powder Diffraction and PDF Analysis, Crystal Growth & Design 16, 4547-4558 (2016), [doi: 10.1021/acs.cgd.6b00660, LillOA]
  9. A. Benazzouz, E. Dudognon, N.T. Correia, V. Molinier, J.-M. Aubry, M. Descamps, Interactions underpinning the plasticization of a polymer matrix: a dynamic and structural analysis of DMP-plasticized cellulose acetate, Cellulose 24, 487-503 (2016), [doi: 10.1007/s10570-016-1148-y, LillOA]
  10. M. Descamps, A. Aumelas, S. Desprez, J. willart, The amorphous state of pharmaceuticals obtained or transformed by milling: Sub-Tg features and rejuvenation, Journal of Non-Crystalline Solids 407, 72-80 (2015), [doi: 10.1016/j.jnoncrysol.2014.08.055, LillOA]
  11. M. Descamps, E. Dudognon, Crystallization from the Amorphous State: Nucleation-Growth Decoupling, Polymorphism Interplay, and the Role of Interfaces, Journal of Pharmaceutical Sciences 103, 2615-2628 (2014), [doi: 10.1002/jps.24016, LillOA]
  12. E. Gué, S. MUSCHERT, J. willart, F. Danede, M. Descamps, E. Delcourt-Debruyne, J. Siepmann, Accelerated fenofibrate release from spray-dried microparticles based on polymer blends, Journal of Drug Delivery Science and Technology 24, 185-190 (2014), [doi: 10.1016/S1773-2247(14)50030-5, LillOA]
  13. A. Mahieu, J. willart, E. Dudognon, F. Danede, M. Descamps, A new protocol to determine the solubility of drugs into polymer matrixes, Molecular Pharmaceutics 10, 560-566 (2013), [doi: 10.1021/mp3002254, LillOA]
  14. E. Dudognon, N. T. Correia, F. Danede, M. Descamps, Solid-Solid Transformation in Racemic Ibuprofen, Pharmaceutical Research 30, 81-89 (2013), [doi: 10.1007/s11095-012-0851-0, LillOA]
  15. A. Mahieu, J. willart, E. Dudognon, M.D. Eddleston, W. Jones, F. Danede, M. Descamps, On the polymorphism of griseofulvin: Identification of two additional polymorphs, Journal of Pharmaceutical Sciences 102, 462-468 (2013), [doi: 10.1002/jps.23349, LillOA]
  16. N. Dujardin, J. willart, E. Dudognon, F. Danede, M. Descamps, Mechanism of Solid State Amorphization of Glucose upon Milling, The Journal of Physical Chemistry B 117, 1437-1443 (2013), [doi: 10.1021/jp3069267, LillOA]
  17. E. Gué, J. willart, S. MUSCHERT, F. Danede, E. Delcourt, M. Descamps, J. Siepmann, Accelerated ketoprofen release from polymeric matrices: Importance of the homogeneity/heterogeneity of excipient distribution, International journal of pharmaceutics 457, 298-307 (2013), [doi: 10.1016/j.ijpharm.2013.09.023, LillOA]
  18. N. Tabary, A. Mahieu, J. willart, E. Dudognon, F. Danede, M. Descamps, m. Bacquet, B. Martel, Characterization of the hidden glass transition of amorphous cyclomaltoheptaose, Carbohydrate research 346, 2193-2199 (2011), [doi: 10.1016/j.carres.2011.07.010, LillOA]
  19. N. Dujardin, E. Dudognon, J. willart, A. Hedoux, Y. Guinet, L. Paccou, M. Descamps, Solid state mutarotation of glucose, J. Phys. Chem. B 115, 1698-1705 (2011), [doi: 10.1021/jp109382j, LillOA]
  20. P. Derollez, E. Dudognon, F. Affouard, F. Danede, N. T. Correia, M. Descamps, Ab initio structure determination of phase II of racemic ibuprofen by X-ray powder diffraction, Acta Crystallographica Section B 66, 76-80 (2010), [doi: 10.1107/S0108768109047363, LillOA]
  21. N. Dujardin, J. willart, E. Dudognon, F. Danede, M. Descamps, First obtaining of glass solutions and phase diagram of glucose with fully tunable anomeric concentration, Journal of Pharmaceutical Sciences 99, 1476 - 1483 (2010), [doi: 10.1002/jps.21900, LillOA]

Liste complète (Le lien peut être lent)

Communications

  1. E. Dudognon, A. Benazzouz, V. Molinier, J.-M. Aubry, M. Descamps, N. T. Correia, Dynamic and structural investigation of interactions at the origin of the plasticization of a polymer matrix: the case of DMP-plasticized Cellulose Acetate, Communication dans un congrès sans actes, 8th International Discussion Meeting on Relaxations in Complex Systems (8IDMRCS), Wisla, Pologne, Juil 2017 [LillOA]
  2. A. Krupa, M. Descamps, J. willart, F. Danede, E. Wyska, R. Jachowicz, The technological solutions to enhance the bioavailability of tadalafil, Communication dans un congrès sans actes, The 1st International Conference on Contemporary Pharmacy Challenges, Wisla, Pologne, Sep 2018 [LillOA]
  3. M. Descamps, INTRODUCTION TO AMORPHOUS SYSTEMS Glass-forming ability and Stability, Conférence invitée, APV ASD Master Class - Abbvie, Ludwigshafen, Allemagne, Nov 2017 [LillOA]
  4. P. Oliveira, J. willart, J. Siepmann, F. Siepmann, M. Descamps, Transformations of dexamethasone drug induced by mechanical milling, Communication dans un congrès sans actes, INCOME 2017 (9th International Conference on Mechanochemistry and Mechanical Alloying), Kosice, Slovaquie, Sep 2017 [LillOA]
  5. M. Descamps, The Amorphous State: to get there, to stay there, to identify and use it., Conférence invitée, Pfizer Stability Workshop, Sandwich, Royaume-Uni, Nov 2016 [LillOA]
  6. E. Gue, J. willart, S. MUSCHERT, F. Danede, M. Descamps, E. Delcourt Debruyne, J. Siepmann, Eudragit® E-Based Matrices for Accelerated Ketoprofen Release in Acidic Media, Poster, AMPTECH 2014 (Advanced Materials and Pharmaceutical TEChnologies), Villeneuve d'Ascq, France, Juil 2014 [LillOA]
  7. E. Gue, S. MUSCHERT, J. willart, F. Danede, E. Delcourt Debruyne, M. Descamps, J. Siepmann, Accelerated Fenofibrate Release from Spray-Dried Microparticles Based on Polymer Blends, Poster, 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Lisbonne, Portugal, Mar 2014 [LillOA]
  8. E. Gue, S. MUSCHERT, J. willart, F. Danede, E. Delcourt Debruyne, M. Descamps, J. Siepmann, Accelerated Ketoprofen Release from Spray-Dried Polymeric Particles, Poster, 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Lisbonne, Portugal, Mar 2014 [LillOA]
  9. E. Gue, J. willart, F. Danede, S. MUSCHERT, M. Descamps, E. Delcourt, J. Siepmann, Accelerated Ketoprofen Release from Eudragit® E-Based Matrices, Communication dans un congrès sans actes, 7th annual PSSRC: Advanced characterization techniques for solid pharmaceutical dosage form, Lille, France, Juil 2013 [LillOA]
  10. E. Gue, J. willart, S. MUSCHERT, F. Danede, M. Descamps, E. Delcourt Debruyne, J. Siepmann, Eudragit® E-Based Matrices for Accelerated Ketoprofen Release in Acidic Media, Poster, 3rd Conference on Innovation in Drug Delivery: Advances in Local Drug Delivery, Pisa, Italie, Sep 2013 [LillOA]

Liste complète (Le lien peut être lent)

 
 
UMET - Unité Matériaux et Transformations
CNRS UMR 8207
Université de Lille
Bâtiment C6
59655 Villeneuve d'Ascq
France
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