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Unité Matériaux et Transformations
CNRS UMR 8207 - Université de Lille

DUDOGNON Emeline
Emeline DUDOGNON
Maître de Conférences
Bâtiment P5 - 213
Unité Matériaux et Transformations
Cité scientifique, Bât. P5
Université de Lille
59655 Villeneuve d'Ascq
France
Tel: +33 (0)3 20 43 69 90
Fax: +33 (0)3 20 43 40 84
Courriel: emeline.dudognon@univ-lille.fr

Recherche

* Dualité cristal/verre : transformations de phases et nucléations basses températures * Matériaux thérapeutiques forcés : amorphisation, transformations polymorphiques et formations d’alliages moléculaires hors équilibre par mécanosynthèse * Mobilité moléculaire dans la zone de la transition vitreuse dans les liquides formateurs de verre.

Enseignement

Enseignement en premier cycle (mécanique des fluides, électrocinétique, optique…) et en deuxième cycle (verres inorganiques, mobilités dans les amorphes) universitaires

Thèses en cours

Thèses soutenues

Derniers dépôts dans dans LillOA (Lille Open Archive)

Publications

  1. E. Dudognon, F. Affouard, J.A. Bama, Molecular Mobility of Terfenadine: Investigation by Dielectric Relaxation Spectroscopy and Molecular Dynamics Simulation, Molecular Pharmaceutics 16;11, 4711-4724 (2019), [doi: 10.1021/acs.molpharmaceut.9b00877, LillOA]
  2. P. Martinetto, P. Bordet, M. Descamps, E. Dudognon, W. Pagnoux, J. willart, Structural Transformations of d -Mannitol Induced by in Situ Milling Using Real Time Powder Synchrotron Radiation Diffraction, Crystal Growth & Design 17, 6111-6122 (2017), [doi: 10.1021/acs.cgd.7b01283, LillOA]
  3. J. willart, E. Dudognon, A. Mahieu, M.D. Eddleston, W. Jones, M. Descamps, The role of cracks in the crystal nucleation process of amorphous griseofulvin, The European Physical Journal Special Topics 226, 837-847 (2017), [doi: 10.1140/epjst/e2016-60358-y, LillOA]
  4. A. Benazzouz, E. Dudognon, N. T. Correia, V. Molinier, J.-M. Aubry, M. Descamps, Interactions underpinning the plasticization of a polymer matrix: a dynamic and structural analysis of DMP-plasticized cellulose acetate, Cellulose 24, 487-503 (2017), [doi: 10.1007/s10570-016-1148-y, LillOA]
  5. P. Bordet, A. Bytchkov, M. Descamps, E. Dudognon, E. Elkaïm, P. Martinetto, W. Pagnoux, A. Poulain, J. willart, Solid State Amorphization of β-Trehalose: A Structural Investigation Using Synchrotron Powder Diffraction and PDF Analysis, Crystal Growth & Design 16, 4547-4558 (2016), [doi: 10.1021/acs.cgd.6b00660, LillOA]
  6. B. Schammé, N. Couvrat, P. Malpeli, E. Dudognon, L. Delbreilh, V. Dupray, E. Dargent, G. Coquerel, Transformation of an active pharmaceutical ingredient upon high-energy milling: A process-induced disorder in Biclotymol, International Journal of Pharmaceutics 499, 67-73 (2016), [doi: 10.1016/j.ijpharm.2015.12.032, LillOA]
  7. A. Benazzouz, E. Dudognon, N.T. Correia, V. Molinier, J.-M. Aubry, M. Descamps, Interactions underpinning the plasticization of a polymer matrix: a dynamic and structural analysis of DMP-plasticized cellulose acetate, Cellulose 24, 487-503 (2016), [doi: 10.1007/s10570-016-1148-y, LillOA]
  8. M. Descamps, E. Dudognon, Crystallization from the Amorphous State: Nucleation-Growth Decoupling, Polymorphism Interplay, and the Role of Interfaces, Journal of Pharmaceutical Sciences 103, 2615-2628 (2014), [doi: 10.1002/jps.24016, LillOA]
  9. A. Mahieu, J. willart, E. Dudognon, M.D. Eddleston, W. Jones, F. Danede, M. Descamps, On the polymorphism of griseofulvin: Identification of two additional polymorphs, Journal of Pharmaceutical Sciences 102, 462-468 (2013), [doi: 10.1002/jps.23349, LillOA]
  10. A. Mahieu, J. willart, E. Dudognon, F. Danede, M. Descamps, A new protocol to determine the solubility of drugs into polymer matrixes, Molecular Pharmaceutics 10, 560-566 (2013), [doi: 10.1021/mp3002254, LillOA]
  11. N. Dujardin, J. willart, E. Dudognon, F. Danede, M. Descamps, Mechanism of Solid State Amorphization of Glucose upon Milling, The Journal of Physical Chemistry B 117, 1437-1443 (2013), [doi: 10.1021/jp3069267, LillOA]
  12. E. Dudognon, N. T. Correia, F. Danede, M. Descamps, Solid-Solid Transformation in Racemic Ibuprofen, Pharmaceutical Research 30, 81-89 (2013), [doi: 10.1007/s11095-012-0851-0, LillOA]
  13. A. Hedoux, Y. Guinet, P. Derollez, E. Dudognon, N. T. Correia, Raman spectroscopy of racemic ibuprofen: Evidence of molecular disorder in phase II, International Journal of Pharmaceutics 421, 45-52 (2011), [doi: 10.1016/j.ijpharm.2011.09.015, LillOA]
  14. N. Tabary, A. Mahieu, J. willart, E. Dudognon, F. Danede, M. Descamps, m. Bacquet, B. Martel, Characterization of the hidden glass transition of amorphous cyclomaltoheptaose, Carbohydrate research 346, 2193-2199 (2011), [doi: 10.1016/j.carres.2011.07.010, LillOA]
  15. N. Dujardin, E. Dudognon, J. willart, A. Hedoux, Y. Guinet, L. Paccou, M. Descamps, Solid state mutarotation of glucose, J. Phys. Chem. B 115, 1698-1705 (2011), [doi: 10.1021/jp109382j, LillOA]
  16. P. Derollez, E. Dudognon, F. Affouard, F. Danede, N. T. Correia, M. Descamps, Ab initio structure determination of phase II of racemic ibuprofen by X-ray powder diffraction, Acta Crystallographica Section B 66, 76-80 (2010), [doi: 10.1107/S0108768109047363, LillOA]
  17. N. Dujardin, J. willart, E. Dudognon, F. Danede, M. Descamps, First obtaining of glass solutions and phase diagram of glucose with fully tunable anomeric concentration, Journal of Pharmaceutical Sciences 99, 1476 - 1483 (2010), [doi: 10.1002/jps.21900, LillOA]
  18. J. willart, N. Dujardin, E. Dudognon, F. Danede, M. Descamps, Amorphization of sugar hydrates upon milling, Carbohydrate research 345, 1613 (2010), [doi: 10.1016/j.carres.2010.04.014, LillOA]

Communications

  1. E. Dudognon, A. Benazzouz, V. Molinier, J.-M. Aubry, M. Descamps, N. T. Correia, Dynamic and structural investigation of interactions at the origin of the plasticization of a polymer matrix: the case of DMP-plasticized Cellulose Acetate, Communication dans un congrès sans actes, 8th International Discussion Meeting on Relaxations in Complex Systems (8IDMRCS), Wisla, Pologne, Juil 2017 [LillOA]
  2. E. Dudognon, Insights from Dielectric Spectroscopy on the physical states reached by milling of an Active Pharmaceutical Ingredient, Communication dans un congrès sans actes, 10th Conference on Broadband Dielectric spectroscopy and its applications, Brussels, Belgique, Aou 2018 [LillOA]
  3. J.A. Bama, E. Dudognon, F. Affouard, Investigation of complex molecular dynamics in multi-component systems, Communication dans un congrès sans actes, BIOFIT MARSEILLE - INTERREG 2 Seas IMODE Project Fourth annual convention, Marseille, France, Déc 2019 [LillOA]
  4. J.A. Bama, E. Dudognon, F. Affouard, Investigation of amorphous solid solution of pharmaceutical interest obtained by grinding, Poster, 17th European Conference on Solid Sate Chemistry (ECSSC17), Villeneuve d'Ascq, France, Sep 2019 [LillOA]
  5. E. Dudognon, Milling as a tool to play with physical state of a pharmaceutical molecule: input from Dielectric Relaxation Spectroscopy, Poster, 17th European Conference on Solid State Chemistry (ECSSC17), Villeneuve d'Ascq, France, Sep 2019 [LillOA]
  6. J.A. Bama, E. Dudognon, F. Affouard, CARACTERISATION D’UN MELANGE PHARMACEUTIQUE PRINCIPE ACTIF-EXCIPIENT POLYMERE, Communication dans un congrès sans actes, 50ème Journées de Calorimétrie et d’Analyse Thermique, Saint-Valéry en Caux, France, Juin 2019 [LillOA]
 
 
UMET - Unité Matériaux et Transformations
CNRS UMR 8207
Université de Lille
Bâtiment C6
59655 Villeneuve d'Ascq
France
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