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Unité Matériaux et Transformations
CNRS UMR 8207 - Université de Lille

DESCAMPS Marc
Marc DESCAMPS
Professeur
Bâtiment P5 - 221
Unité Matériaux et Transformations
Cité scientifique, Bât. P5
Université de Lille
59655 Villeneuve d'Ascq
France
Tel: +33 (0)3 20 43 49 79
Fax: +33 (0)3 20 43 40 84
Courriel: marc.descamps@univ-lille.fr

Recherche

Cristaux moléculaires désordonnés : Cristaux vitreux, cinétiques de transformations de phase, mobilité moléculaire à l’état cristallin. Verres et transition vitreuse de composés moléculaires. Physique des Solides Pharmaceutiques. Matériaux moléculaires forcés (transformations induites par broyage)

Edition

Thèses soutenues

Derniers dépôts dans dans LillOA (Lille Open Archive)

Publications

  1. P. Oliveira, J. willart, J. Siepmann, F. Siepmann, M. Descamps, Using Milling To Explore Physical States: The Amorphous and Polymorphic Forms of Dexamethasone, Crystal Growth & Design 18, 1748-1757 (2018), [doi: 10.1021/acs.cgd.7b01664, LillOA]
  2. M. Descamps, J. willart, Scaling laws and size effects for amorphous crystallization kinetics: Constraints imposed by nucleation and growth specificities, International journal of pharmaceutics 542, 186-195 (2018), [doi: 10.1016/j.ijpharm.2018.03.001, LillOA]
  3. A. Mahieu, J. willart, M. Guerain, P. Derollez, F. Danede, M. Descamps, Structure determination of phase II of the antifungal drug griseofulvin by powder X-ray diffraction, Acta Crystallographica Section C Structural Chemistry 74, 321-324 (2018), [doi: 10.1107/S2053229618001845, LillOA]
  4. E. Elisei, J. willart, F. Danede, J. Siepmann, F. Siepmann, M. Descamps, Crystalline Polymorphism Emerging From a Milling-Induced Amorphous Form: The Case of Chlorhexidine Dihydrochloride, Journal of Pharmaceutical Sciences 107, 121-126 (2018), [doi: 10.1016/j.xphs.2017.07.003, LillOA]
  5. A. Benazzouz, E. Dudognon, N. Correia, V. Molinier, J. Aubry, M. Descamps, Interactions underpinning the plasticization of a polymer matrix: a dynamic and structural analysis of DMP-plasticized cellulose acetate, Cellulose 24, 487-503 (2016), [doi: 10.1007/s10570-016-1148-y, LillOA]
  6. A. Krupa, M. Descamps, J. willart, B. Strach, E. Wyska, R. Jachowicz, F. Danede, High-Energy Ball Milling as Green Process To Vitrify Tadalafil and Improve Bioavailability, Molecular Pharmaceutics 13, 3891-3902 (2016), [doi: 10.1021/acs.molpharmaceut.6b00688, LillOA]
  7. A. Krupa, M. Descamps, J. willart, R. Jachowicz, F. Danede, High energy ball milling and supercritical carbon dioxide impregnation as co-processing methods to improve dissolution of tadalafil, European Journal of Pharmaceutical Sciences 95, 130-137 (2016), [doi: 10.1016/j.ejps.2016.05.007, LillOA]
  8. E. Shalaev, K. Wu, S. Shamblin, J. Krzyzaniak, M. Descamps, Crystalline mesophases: Structure, mobility, and pharmaceutical properties, Advanced Drug Delivery Reviews 100, 194-211 (2016), [doi: 10.1016/j.addr.2016.04.002, LillOA]
  9. M. Descamps, J. willart, Perspectives on the amorphisation/milling relationship in pharmaceutical materials, Advanced Drug Delivery Reviews 100, 51-66 (2016), [doi: 10.1016/j.addr.2016.01.011, LillOA]
  10. M. Descamps, Amorphous Pharmaceutical Solids, Advanced Drug Delivery Reviews 100, 1-2 (2016), [doi: 10.1016/j.addr.2016.04.011, LillOA]
  11. N. Tabary, M. Garcia-Fernandez, F. Danede, M. Descamps, B. Martel, J. willart, Determination of the glass transition temperature of cyclodextrin polymers, Carbohydrate polymers 148, 172-180 (2016), [doi: 10.1016/j.carbpol.2016.04.032, LillOA]
  12. M. Descamps, A. Aumelas, S. Desprez, J. willart, The amorphous state of pharmaceuticals obtained or transformed by milling: Sub-Tg features and rejuvenation, Journal of Non-Crystalline Solids 407, 72-80 (2015), [doi: 10.1016/j.jnoncrysol.2014.08.055, LillOA]
  13. Y. Jallouli, J. willart, F. Siepmann, M. Descamps, F. Danede, J. Siepmann, Preparation of polymeric fenofibrate formulations with accelerated drug release: Solvent evaporation versus co-grinding, Journal of Drug Delivery Science and Technology 30, 397-407 (2015), [doi: 10.1016/j.jddst.2015.07.013, LillOA]
  14. E. Elisei, M. Filibian, P. Carretta, S. Colombo Serra, F. Tedoldi, J. willart, M. Descamps, A. Cesàro, Dynamic nuclear polarization of a glassy matrix prepared by solid state mechanochemical amorphization of crystalline substances, Chemical Communications 51, 2080-2083 (2015), [doi: 10.1039/C4CC08348B, LillOA]
  15. E. Gué, S. MUSCHERT, J. willart, F. Danede, M. Descamps, E. Delcourt-Debruyne, J. Siepmann, Accelerated fenofibrate release from spray-dried microparticles based on polymer blends, Journal of Drug Delivery Science and Technology 24, 185-190 (2014), [doi: 10.1016/S1773-2247(14)50030-5, LillOA]
  16. E. Gue, S. MUSCHERT, J. willart, F. Danede, E. Delcourt-Debruyne, M. Descamps, J. Siepmann, Accelerated ketoprofen release from spray-dried polymeric particles: importance of phase transitions and excipient distribution, Drug development and industrial pharmacy 41, 838-850 (2014), [doi: 10.3109/03639045.2014.908902, LillOA]
  17. M. Descamps, A. Aumelas, S. Desprez, J. willart, The amorphous state of pharmaceuticals obtained or transformed by milling: Sub-Tg features and rejuvenation, Journal of Non-Crystalline Solids (2014), [doi: 10.1016/j.jnoncrysol.2014.08.055, LillOA]
  18. M. Descamps, A. Decroix, Polymorphism and disorder in caffeine: Dielectric investigation of molecular mobilities, Journal of Molecular Structure 1078, 165-173 (2014), [doi: 10.1016/j.molstruc.2014.04.042, LillOA]
  19. E. Gué, J. willart, S. MUSCHERT, F. Danede, E. Delcourt, M. Descamps, J. Siepmann, Accelerated ketoprofen release from polymeric matrices: Importance of the homogeneity/heterogeneity of excipient distribution, International journal of pharmaceutics 457, 298-307 (2013), [doi: 10.1016/j.ijpharm.2013.09.023, LillOA]
  20. J. willart, M. Durand, L. Briggner, A. Marx, F. Danede, M. Descamps, Solid-state amorphization of linaprazan by mechanical milling and evidence of polymorphism, Journal of Pharmaceutical Sciences 102, 2214-2220 (2013), [doi: 10.1002/jps.23573, LillOA]

Liste complète (Le lien peut être lent)

Communications

  1. A. Krupa, M. Descamps, J. willart, F. Danede, E. Wyska, R. Jachowicz, The technological solutions to enhance the bioavailability of tadalafil, Communication dans un congrès sans actes, The 1st International Conference on Contemporary Pharmacy Challenges, Wisla, Pologne, Sep 2018 [LillOA]
  2. M. Descamps, INTRODUCTION TO AMORPHOUS SYSTEMS Glass-forming ability and Stability, Conférence invitée, APV ASD Master Class - Abbvie, Ludwigshafen, Allemagne, Nov 2017 [LillOA]
  3. P. Oliveira, J. willart, J. Siepmann, F. Siepmann, M. Descamps, Transformations of dexamethasone drug induced by mechanical milling, Communication dans un congrès sans actes, INCOME 2017 (9th International Conference on Mechanochemistry and Mechanical Alloying), Kosice, Slovaquie, Sep 2017 [LillOA]
  4. M. Descamps, The Amorphous State: to get there, to stay there, to identify and use it., Conférence invitée, Pfizer Stability Workshop, Sandwich, Royaume-Uni, Nov 2016 [LillOA]
  5. E. Gue, S. MUSCHERT, J. willart, F. Danede, E. Delcourt Debruyne, M. Descamps, J. Siepmann, Accelerated Fenofibrate Release from Spray-Dried Microparticles Based on Polymer Blends, Poster, 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Lisbonne, Portugal, Mar 2014 [LillOA]
  6. E. Gue, S. MUSCHERT, J. willart, F. Danede, E. Delcourt Debruyne, M. Descamps, J. Siepmann, Accelerated Ketoprofen Release from Spray-Dried Polymeric Particles, Poster, 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Lisbonne, Portugal, Mar 2014 [LillOA]
  7. E. Gue, J. willart, S. MUSCHERT, F. Danede, M. Descamps, E. Delcourt Debruyne, J. Siepmann, Eudragit® E-Based Matrices for Accelerated Ketoprofen Release in Acidic Media, Poster, AMPTECH 2014 (Advanced Materials and Pharmaceutical TEChnologies), Villeneuve d'Ascq, France, Juil 2014 [LillOA]
  8. P. Oliveira, J. willart, J. Siepmann, F. Siepmann, M. Descamps, Solid state transformations of dexamethasone induced by milling, Communication dans un congrès sans actes, 2nd European Conference on Pharmaceutics, Kraków, Pologne, Avr 2017 [LillOA]
  9. M. Descamps, J. willart, Milling of amorphous molecular and pharmaceutical compounds, Communication dans un congrès sans actes, 15èmes Journées de la Matière Condensée, Bordeaux, France, Aou 2016 [LillOA]
  10. E. Gue, J. willart, F. Danede, S. MUSCHERT, M. Descamps, E. Delcourt, J. Siepmann, Accelerated Ketoprofen Release from Eudragit® E-Based Matrices, Communication dans un congrès sans actes, 7th annual PSSRC: Advanced characterization techniques for solid pharmaceutical dosage form, Lille, France, Juil 2013 [LillOA]

Liste complète (Le lien peut être lent)

 
 
UMET - Unité Matériaux et Transformations
CNRS UMR 8207
Université de Lille
Bâtiment C6
59655 Villeneuve d'Ascq
France
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