UMET - Matériaux Moléculaires et Thérapeutiques Group leader: Marc Descamps

Membres

Faculty and CNRS researchers: Frédéric Affouard, Laurent Carpentier, Eric Cochin, Natalia Correia, Patrick Derollez, Marc Descamps, Emeline Dudognon, Yannick Guinet, Alain Hédoux, Nicolas Tabary, Laurent-Charles Valdes, Jean-François Willart Staff: Florence Danède, Alexis Mazurier, Laurent Paccou, Isabelle Schack ATER and post-docs: Giuseppe Bellavia PhD students: Samira Achir, Rémy Dubois, Joseph Gerges, Aurélien Mahieu, Martin Thierry Ottou Abe, William Pagnoux, Ahmed Mourad Salah

Our research activity concerns the physical state of molecular materials composed of small molecules and/or of biological molecules under various stresses: temperature, pressure, grinding, dehydration. The main goal is to analyse the situations of metastabilities, the glassy states and the phase transformations and out-of-equilibrium evolutions induced by these stresses. The investigated materials are also found in the pharmaceuticals and food domains.Our works have direct implication in the control of the formulation and the stability of these materials with direct consequences on their bioavailability.

Our research activities are also linked to the Matériaux Pharmaceutiques program of the Master Physique de Lille. Details on the program can be downloaded as PDF here.

Active projects

• Physics of the glass transition

  Dynamical heterogeneities, nucleation and nanostructures, glassy crystals, polyAmorphism

  Contacts : F. Affouard, Laurent Carpentier, M. Descamps

• Driven molecular materials

  Transformations induced by grinding and dehydration

  Contacts : Jean-François Willart, Marc Descamps, Emeline Dudognon

• Protection of biological materials

  Mechanisms of stabilization of sugars, cold and thermal denaturation

  The activities are undertaken in the framework of the ANR PCV research project 2007-2011 BIOSTAB “Optimisation of the stability of biological materials for novel therapeutic strategies”.

  Contacts : Alain Hédoux, Yannick Guinet, Frédéric Affouard

• Improving Drugs Efficacy and Availability (IDEA)

  Cross-border cooperation programme 2007-2013
  INTERREG IVA “2 Mers Seas Zeeën”

  Contacts: Marc Descamps, Frédéric Affouard