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Unité Matériaux et Transformations
CNRS UMR 8207 - Université de Lille

DUDOGNON Emeline
Emeline DUDOGNON
Maître de Conférences Université de Lille, FST-Dép Physique
Bâtiment P5 - 213
Unité Matériaux et Transformations
Cité scientifique, Bât. P5
Université de Lille
59655 Villeneuve d'Ascq
France
Tel: +33 (0)3 20 43 69 90
Fax: +33 (0)3 20 43 40 84
Courriel Envoyer un mel à  Emeline DUDOGNON: Envoyer un mel à Emeline DUDOGNON
Identifiant ORCID 0000-0003-4176-1925: 0000-0003-4176-1925

Recherche

* Dualité cristal/verre : transformations de phases et nucléations basses températures * Matériaux thérapeutiques forcés : amorphisation, transformations polymorphiques et formations d’alliages moléculaires hors équilibre par mécanosynthèse * Mobilité moléculaire dans la zone de la transition vitreuse dans les liquides formateurs de verre.

Enseignement

Enseignement en premier cycle (mécanique des fluides, électrocinétique, optique…) et en deuxième cycle (verres inorganiques, mobilités dans les amorphes) universitaires

Thèses en cours

Thèses soutenues

Derniers dépôts dans dans LillOA (Lille Open Archive)

Publications

  1. E. Dudognon, F. Danede, M. Guerain, Milling-induced Phase Transformations, Underlying Mechanisms and Resulting Physical States in an Enantiotropic System: the Case of Bezafibrate, Crystal Growth & Design 22;1, 363-378 (2022), [doi: 10.1021/acs.cgd.1c00997, LillOA]
  2. J.A. Bama, E. Dudognon, F. Affouard, Impact of Low Concentration of Strongly Hydrogen-Bonded Water Molecules on the Dynamics of Amorphous Terfenadine: Insights from Molecular Dynamics Simulations and Dielectric Relaxation Spectroscopy, The Journal of Physical Chemistry B 125;40, p. 11292-11307 (2021), [doi: 10.1021/acs.jpcb.1c06087, LillOA]
  3. E. Dudognon, F. Affouard, J.A. Bama, Molecular Mobility of Terfenadine: Investigation by Dielectric Relaxation Spectroscopy and Molecular Dynamics Simulation, Molecular Pharmaceutics 16;11, 4711-4724 (2019), [doi: 10.1021/acs.molpharmaceut.9b00877, LillOA]
  4. J.-F. willart, E. Dudognon, A. Mahieu, M.D. Eddleston, W. Jones, M. Descamps, The role of cracks in the crystal nucleation process of amorphous griseofulvin, The European Physical Journal Special Topics 226, 837-847 (2017), [doi: 10.1140/epjst/e2016-60358-y, LillOA]
  5. P. Martinetto, P. Bordet, M. Descamps, E. Dudognon, W. Pagnoux, J.-F. willart, Structural Transformations of d -Mannitol Induced by in Situ Milling Using Real Time Powder Synchrotron Radiation Diffraction, Crystal Growth & Design 17, 6111-6122 (2017), [doi: 10.1021/acs.cgd.7b01283, LillOA]
  6. A. Benazzouz, E. Dudognon, N. T. Correia, V. Molinier, J.-M. Aubry, M. Descamps, Interactions underpinning the plasticization of a polymer matrix: a dynamic and structural analysis of DMP-plasticized cellulose acetate, Cellulose 24, 487-503 (2017), [doi: 10.1007/s10570-016-1148-y, LillOA]
  7. B. Schammé, N. Couvrat, P. Malpeli, E. Dudognon, L. Delbreilh, V. Dupray, E. Dargent, G. Coquerel, Transformation of an active pharmaceutical ingredient upon high-energy milling: A process-induced disorder in Biclotymol, International Journal of Pharmaceutics 499, 67-73 (2016), [doi: 10.1016/j.ijpharm.2015.12.032, LillOA]
  8. P. Bordet, A. Bytchkov, M. Descamps, E. Dudognon, E. Elkaïm, P. Martinetto, W. Pagnoux, A. Poulain, J.-F. willart, Solid State Amorphization of β-Trehalose: A Structural Investigation Using Synchrotron Powder Diffraction and PDF Analysis, Crystal Growth & Design 16, 4547-4558 (2016), [doi: 10.1021/acs.cgd.6b00660, LillOA]
  9. M. Descamps, E. Dudognon, Crystallization from the Amorphous State: Nucleation-Growth Decoupling, Polymorphism Interplay, and the Role of Interfaces, Journal of Pharmaceutical Sciences 103, 2615-2628 (2014), [doi: 10.1002/jps.24016, LillOA]
  10. N. Dujardin, J.-F. willart, E. Dudognon, F. Danede, M. Descamps, Mechanism of Solid State Amorphization of Glucose upon Milling, The Journal of Physical Chemistry B 117, 1437-1443 (2013), [doi: 10.1021/jp3069267, LillOA]
  11. E. Dudognon, N. T. Correia, F. Danede, M. Descamps, Solid-Solid Transformation in Racemic Ibuprofen, Pharmaceutical Research 30, 81-89 (2013), [doi: 10.1007/s11095-012-0851-0, LillOA]
  12. A. Mahieu, J.-F. willart, E. Dudognon, M.D. Eddleston, W. Jones, F. Danede, M. Descamps, On the polymorphism of griseofulvin: Identification of two additional polymorphs, Journal of Pharmaceutical Sciences 102, 462-468 (2013), [doi: 10.1002/jps.23349, LillOA]
  13. A. Mahieu, J.-F. willart, E. Dudognon, F. Danede, M. Descamps, A new protocol to determine the solubility of drugs into polymer matrixes, Molecular Pharmaceutics 10, 560-566 (2013), [doi: 10.1021/mp3002254, LillOA]
  14. A. Hedoux, Y. Guinet, P. Derollez, E. Dudognon, N. T. Correia, Raman spectroscopy of racemic ibuprofen: Evidence of molecular disorder in phase II, International Journal of Pharmaceutics 421, 45-52 (2011), [doi: 10.1016/j.ijpharm.2011.09.015, LillOA]
  15. N. Dujardin, E. Dudognon, J.-F. willart, A. Hedoux, Y. Guinet, L. Paccou, M. Descamps, Solid state mutarotation of glucose, J. Phys. Chem. B 115, 1698-1705 (2011), [doi: 10.1021/jp109382j, LillOA]
  16. N. Tabary, A. Mahieu, J.-F. willart, E. Dudognon, F. Danede, M. Descamps, m. Bacquet, B. Martel, Characterization of the hidden glass transition of amorphous cyclomaltoheptaose, Carbohydrate research 346, 2193-2199 (2011), [doi: 10.1016/j.carres.2011.07.010, LillOA]
  17. P. Derollez, E. Dudognon, F. Affouard, F. Danede, N. T. Correia, M. Descamps, Ab initio structure determination of phase II of racemic ibuprofen by X-ray powder diffraction, Acta Crystallographica Section B 66, 76-80 (2010), [doi: 10.1107/S0108768109047363, LillOA]
  18. N. Dujardin, J.-F. willart, E. Dudognon, F. Danede, M. Descamps, First obtaining of glass solutions and phase diagram of glucose with fully tunable anomeric concentration, Journal of Pharmaceutical Sciences 99, 1476 - 1483 (2010), [doi: 10.1002/jps.21900, LillOA]
  19. J.-F. willart, N. Dujardin, E. Dudognon, F. Danede, M. Descamps, Amorphization of sugar hydrates upon milling, Carbohydrate research 345, 1613 (2010), [doi: 10.1016/j.carres.2010.04.014, LillOA]

Communications

  1. p. Bordet, P. Martinetto, P. Martinetto, J.-F. Willart, M. Descamps, E. Dudognon, In-situ powder diffraction study of molecular compounds under high energy milling: from amorphization to solid state transformation, Communication dans un congrès sans actes, EPDIC 16 (16th European Powder Diffraction Conference), Edinburgh, Scotland, Mar 2024 [LillOA]
  2. J.-F. Willart, p. Bordet, M. Descamps, E. Dudognon, P. Martinetto, W. Pagnoux, Kinetics of polymorphic transformations of pharmaceuticals induced by mechanical milling, Communication dans un congrès sans actes, ISMANAM 2018 (25th international Symposium on Metastable, Amorphous and Nanostructured Materials), Rome, Mar 2024 [LillOA]
  3. p. Bordet, P. Martinetto, W. Pagnoux, J.-F. Willart, M. Descamps, E. Dudognon, Etude in-situ de composés moléculaires sous broyage à haute énergie: de l'amorphisation à la transformation à l'état solide, Communication dans un congrès sans actes, AFC 2018 (16th European Powder Diffraction Conference), Lyon, Mar 2024 [LillOA]
  4. J.-F. Willart, p. Bordet, P. Martinetto, E. Dudognon, J. Siepmann, F. Siepmann, Solid state transformations of pharmaceuticals induced by milling: Experimental and numerical kinetics investigations, Communication dans un congrès sans actes, INCOME 2020 (9th International Conference on Mechanochemistry and Mechanical Alloying, Cagliari, Mar 2024 [LillOA]
  5. M. Descamps, J.-F. Willart, E. Dudognon, Milling As a Tool to Manipulate and Screen Amorphism and Polymorphism, Conférence invitée, 9th IDMRCS (9th International discussion meeting on relaxations in complex systems), Tsukuba, Mar 2024 [LillOA]
  6. J.A. Bama, E. Dudognon, F. Affouard, Impact of very low concentration of water on the dynamics of amorphous pharmaceuticals, Conférence invitée, International Conference on Science and Technology of Pharmaceutical Glass, Tsukuba, Japon, Aou 2023 [LillOA]
  7. N. Zupan, S. Van de Steene, T. De Beer, A. Mullertz, E. Dudognon, S. Florin Muschert, Polymeric matrices for controlled release of Glibenclamide: Miscibility and dissolution properties, Communication dans un congrès sans actes, 17th PSSRC Annual Symposium, Cambridge, Royaume-Uni, Aou 2023 [LillOA]
  8. N. Zupan, S. Van de Steene, T. De Beer, E. Dudognon, S. Florin Muschert, Challenges in assessing polymer miscibility in pharmaceutical hot-melt extrudates, Poster, 4th European Conference on Pharmaceutics, Marseille, France, Mar 2023 [LillOA]
  9. E. Dudognon, Apport de la spectroscopie de relaxation diélectrique pour la détection d'hétérogénéités structurales dans des matériaux d'intérêt pharmaceutique, Communication dans un congrès sans actes, Colloque Relations structures/propriétés Electriques dans les Polymères & Composites (GDR REEPOS 2023) & 3eme colloque Français sur la Spectroscopie Diélectrique appliquée aux Matériaux SDM 3, Toulouse, France, Juin 2023 [LillOA]
  10. S. Samsoen, E. Dudognon, D. Fournier, G. Le Fer, P. Woisel, F. Affouard, Characterization of Curcumin/PVP amorphous solid dispersions, Poster, 4th European Conference on Pharmaceutics, Marseille, France, Mar 2023 [LillOA]

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UMET - Unité Matériaux et Transformations
CNRS UMR 8207
Université de Lille
Bâtiment C6
59655 Villeneuve d'Ascq
France
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