UMET - Liste des communicatons de Jean-François WILLART

Research seminars

  1. J.-F. willart, Solid state amorphization of pharmaceuticals induced by mechanical milling, AstraZeneca, Göteborg, Göteborg, Suède, Oct 2018 [LillOA]
  2. J.-F. willart, Physical stability of amorphous solid dispersion, AstraZeneca, Göteborg, Göteborg, Suède, Oct 2018 [LillOA]

Invited presentations

  1. J.-F. Willart, Mechanical milling: A useful tool to determine the solubility curve of drugs into polymers, Mini-Symposium on Amorphous Solid Dispersions, Louvain (Université Catholique ), Belgique, Mar 2024 [LillOA]
  2. M. Descamps, J.-F. Willart, E. Dudognon, Milling As a Tool to Manipulate and Screen Amorphism and Polymorphism, 9th IDMRCS (9th International discussion meeting on relaxations in complex systems), Tsukuba, Japon, Mar 2024 [LillOA]
  3. M. Descamps, J.-F. Willart, The Glass Transition of Glassy crystals: Structural Nature of Critical Slowdown & Aging, The Glass Transition of Glassy crystals: Structural Nature of Critical Slowdown & Aging, Chiba, Japon, Mar 2024 [LillOA]
  4. L.-V. Roca Paixao, F. Ngono Mebenga, J.-F. willart, G.J. Cuello, M. Jimenez-Ruiz, N. T. Correia, F. Affouard, Manipulation of the crystalline and amorphous physical states of pharmaceutical materials: possibilities, limits and challenges, 32nd European Crystallographic Meeting (ECM32), Vienna, Autriche, Aug 2019 [LillOA]
  5. M. Descamps, J.-F. willart, Solid State Amorphization Of Pharmaceuticals Poorly Soluble drugs: Exploiting the amorphous state, 3° ALMAC/UCC Joint Symposium, CORK, Irlande, Sep 2013 [LillOA]
  6. M. Descamps, J.-F. willart, Perspective on Driven Molecular Materials, Freeze Drying of Pharmaceuticals and Biologicals, Garmisch-Partenkirchen, Allemagne, Oct 2010 [LillOA]
  7. M. Descamps, J.-F. willart, Pharmaceutical processing: a physical perspective on induced transformations and water involvement, Studium Conferences, Orléans, France, Jun 2012 [LillOA]

Oral presentations

  1. p. Bordet, P. Martinetto, J.-F. Willart, M. Descamps, E. Dudognon, In-situ powder diffraction study of molecular compounds under high energy milling: from amorphization to solid state transformation, EPDIC 16 (16th European Powder Diffraction Conference), Edinburgh, Scotland, Royaume-Uni, Mar 2024 [LillOA]
  2. J.-F. Willart, p. Bordet, M. Descamps, E. Dudognon, P. Martinetto, W. Pagnoux, Kinetics of polymorphic transformations of pharmaceuticals induced by mechanical milling, ISMANAM 2018 (25th international Symposium on Metastable, Amorphous and Nanostructured Materials), Rome, Italie, Mar 2024 [LillOA]
  3. p. Bordet, P. Martinetto, W. Pagnoux, J.-F. Willart, M. Descamps, E. Dudognon, Etude in-situ de composés moléculaires sous broyage à haute énergie: de l'amorphisation à la transformation à l'état solide, AFC 2018 (16th European Powder Diffraction Conference), Lyon, France, Mar 2024 [LillOA]
  4. M. Descamps, J.-F. Willart, Size effects on amorphous crystallization kinetics: Constraints imposed by nucleation and growth specificities, JMC 2018, Jjournées de la Matière Condensée, Grenoble (27-31 août 2018), Grenoble, France, Mar 2024 [LillOA]
  5. J.-F. Willart, p. Bordet, P. Martinetto, E. Dudognon, J. Siepmann, F. Siepmann, Solid state transformations of pharmaceuticals induced by milling: Experimental and numerical kinetics investigations, INCOME 2020 (9th International Conference on Mechanochemistry and Mechanical Alloying, Cagliari, Italie, Mar 2024 [LillOA]
  6. C. Henaff, J. Siepmann, F. Siepmann, J.-F. Willart, Amorphization and solubility enhancement: the peculiar case of chlorhexidine free base, 17th PSSRC: Pharmaceutical Solid State Research Cluster, Cambridge (GB), Royaume-Uni, Mar 2024 [LillOA]
  7. C. Henaff, J. Siepmann, F. Siepmann, J.-F. Willart, Exploration du polymorphisme de la riboflavine par broyage mécanique, Conférence International Matériaux 2022, Lille, France, Mar 2024 [LillOA]
  8. A. Krupa, M. Descamps, J.-F. willart, F. Danede, E. Wyska, R. Jachowicz, The technological solutions to enhance the bioavailability of tadalafil, The 1st International Conference on Contemporary Pharmacy Challenges, Wisla, Pologne, Sep 2018 [LillOA]
  9. M. Latreche, J.-F. Willart, A. Hedoux, Efficient solid state transformation protocol to determine the solubility of drugs into polymers, The 1st International Conference on Contemporary Pharmacy Challenges, Wisla, Pologne, Sep 2018 [LillOA]
  10. F. Ngono Mebenga, F. Affouard, J.-F. willart, G. Cuello, M. Jimenez-Ruiz, Impact of the amorphisation routes on physical properties of amorphous materials, Journées de la Matière Condensée (JMC 2018), Grenoble, France, Aug 2018 [LillOA]
  11. F. Ngono Mebenga, F. Affouard, J.-F. willart, Physico-chemical properties of amorphous lactulose: role of water, 1res Journées Scientifiques du GDR 2035 SolvATE, Nancy, France, May 2018 [LillOA]
  12. F. Affouard, J.-F. willart, F. Ngono Mebenga, G. Cuello, M. Jimenez-Ruiz, Investigations of physical properties of amorphous materials obtained from different routes, 8th International Discussion Meeting on Relaxations in Complex Systems (8IDMRCS), Wisla, Pologne, Jul 2017 [LillOA]
  13. F. Affouard, J.-F. willart, F. Ngono Mebenga, G. Cuello, M. Jimenez-Ruiz, Investigations of physical properties of amorphous materials using neutron scattering experiments, Journées de la Diffusion Neutronique (JDN2017), Carry le Rouet, France, May 2017 [LillOA]
  14. F. Affouard, J.-F. willart, F. Ngono Mebenga, G.J. Cuello, M. Jimenez-Ruiz, Physical and chemical stability of amorphous lactulose obtained from different routes: the role of water, Journée Solvatation, Villeneuve d'Ascq, France, May 2017 [LillOA]
  15. F. Affouard, J.-F. willart, F. Ngono Mebenga, G.J. Cuello, M. Jimenez-Ruiz, Structural investigation of amorphous pharmaceuticals by neutron diffraction experiment, Spanish Neutron Users Society Meeting, Bilbao, Espagne, Jun 2016 [LillOA]
  16. P. Oliveira, J.-F. willart, J. Siepmann, F. Siepmann, M. Descamps, Transformations of dexamethasone drug induced by mechanical milling, INCOME 2017 (9th International Conference on Mechanochemistry and Mechanical Alloying), Kosice, Slovaquie, Sep 2017 [LillOA]
  17. P. Oliveira, J.-F. willart, J. Siepmann, F. Siepmann, M. Descamps, Solid state transformations of dexamethasone induced by milling, 2nd European Conference on Pharmaceutics, Kraków, Pologne, Apr 2017 [LillOA]
  18. A. Krupa, M. Descamps, J.-F. willart, F. Danede, R. Jachowich, Vitrification of tadalafil by co-milling with soluplus, JCAT 46 - Journées de Calorimétrie et d'Analyse Thermique, Montpellier, France, May 2015 [LillOA]
  19. E. Gue, J.-F. willart, F. Danede, S. MUSCHERT, M. Descamps, E. Delcourt, J. Siepmann, Accelerated Ketoprofen Release from Eudragit® E-Based Matrices, 7th annual PSSRC: Advanced characterization techniques for solid pharmaceutical dosage form, Lille, France, Jul 2013 [LillOA]
  20. M. Descamps, J.-F. willart, Milling of amorphous molecular and pharmaceutical compounds, 15èmes Journées de la Matière Condensée, Bordeaux, France, Aug 2016 [LillOA]
  21. G. Bellavia, J.-F. willart, L.-E. Briggner, A. Marx, M. Descamps, NATURE OF THE AMORPHOUS STATE OBTAINED BY MILLING: A CASE STUDY, 7 IDMRCS, Barcelone, Espagne, Jul 2013 [LillOA]
  22. G. Bellavia, J.-F. willart, L.-E. Briggner, A. Marx, M. Descamps, . marx, NATURE AND SPECIFIC FEATURES OF THE AMORPHOUS STATE OBTAINED BY MILLING: A CASE STUDY, 7 PSSRC, Lille, France, Jul 2013 [LillOA]
  23. J.-F. willart, M. Descamps, Dualité cristal/amorphe des matériaux pharmaceutiques broyés: exemple de la griseofulvine, 43èmes Journées de Calorimétrie et d'Analyse Thermique, Toulouse, France, May 2012 [LillOA]
  24. J.-F. willart, Structural transformations of pharmaceuticals upon milling: open questions, Workshop Pharmaceutical materials and drug efficacy, Villeneuve d'Ascq, France, Jul 2011 [LillOA]
  25. M. Descamps, J.-F. willart, A physical perspertive of process induced phase and glass transitions of pharmaceuticals, PTM 2010 : Tenth International Workshop on Non Crystalline Solids, Avignon, France, Jun 2010 [LillOA]

Poster presentations

  1. A. Krupa, F. Danede, A. Węgrzyn, J.-F. Willart, How to enhance the solubility of bosentan?, 13th Central European Symposium on Pharmaceutical Technology, Gdansk, Pologne, Mar 2024 [LillOA]
  2. A. Krupa, F. Danede, I. Kondera, A. Węgrzyn, J.-F. Willart, The co-milled molecular alloys bosnetan / copovidone as a green way to create supersaturation in the git, AAPS PharmSci 360, Philadelphia, Etats-Unis d'Amérique, Mar 2024 [LillOA]
  3. C. Henaff, J. Siepmann, F. Siepmann, J.-F. Willart, Solid state amorphization of riboflavin upon milling, 15th PSSRC: Pharmaceutical Solid State Research Cluster, Online, Mar 2024 [LillOA]
  4. C. Henaff, J. Siepmann, F. Siepmann, J.-F. Willart, Solid state amorphization of Chlorhexidine chlorhexidine upon milling, 16th PSSRC: Pharmaceutical Solid State Research Cluster, Helsinki, Finlande, Mar 2024 [LillOA]
  5. J.-F. Willart, S. Ouerghemmi, N. Descamps, P. Heijboer, M. Descamps, Mécanisme de liquéfaction du glucose, Conférence International Matériaux 2022, Lille, France, Mar 2024 [LillOA]
  6. A. Dupont, M. Guerain, J.-F. Willart, Cinétique de transformation de phase de produits pharmaceutiques sous broyage, Conférence International Matériaux 2022, Lille, France, Mar 2024 [LillOA]
  7. A. Dupont, M. Guerain, J.-F. Willart, Effet de la température sur les cinétiques d'amorphisation des matériaux moléculaires par broyage mécanique, Conférence International Matériaux 2022, Lille, France, Mar 2024 [LillOA]
  8. D. Strojewski, S. Lalik, F. Danede, M. Marzec, J.-F. Willart, A. Krupa, Design of co-amorphous fixed-dose combinations of bosentan and sildenafil base, 14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Vienne (Austria), Autriche, Mar 2024 [LillOA]
  9. C. Henaff, J. Siepmann, F. Siepmann, J.-F. Willart, Amorphous chlorhexidine (free base) dissolves less rapidly compared to crystalline, 14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Vienne (Austria), Autriche, Mar 2024 [LillOA]
  10. Y. Bedulho Das Lages, N. Milanino, J. Verin, J.-F. Willart, F. Danede, C. Vincent, P. Bawuah, J. Zeitler, F. Siepmann, J. Siepmann, EVA implants for controlled drug delivery to the inner ear, 14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Vienne (Austria), Autriche, Mar 2024 [LillOA]
  11. F. Tamani, C. Bassand, M.H.-B. Yelles, J.-F. willart, F. Danede, F. Siepmann, J. Siepmann, How single PLGA microparticles behave, 3rd European Conference on Pharmaceutics, Bologne, Italie, Mar 2018 [LillOA]
  12. M.-J. Garcia Fernandez, N. Tabary, F. Chai, J.-F. willart, N. Blanchemain, M.-P. Leterme Flament, B. Martel, Cyclodextrin polymer as a multifunctional excipient in tablet formulations, 19th International Cyclodextrin Symposium (ICS 2018)., Tokyo, Japon, Apr 2018 [LillOA]
  13. T. Rongthong, M. Gehrke, P. Oliveira, F. Danede, J.-F. willart, C. Vincent, F. Siepmann, J. Siepmann, Silicone matrices for controlled drug delivery to the inner ear: Effects of the drug form and agglomerates, 11th world meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical technology, Granada, Espagne, Mar 2018 [LillOA]
  14. M.-J. Garcia Fernandez, N. Tabary, J.-F. willart, F. Chai, N. Blanchemain, M.-P. Leterme Flament, B. Martel, 2.Multifunctional pharmaceutical excipient in tablet formulation based on citric acid-cyclodextrin polymer, 5th European Cyclodextrin Conference (EUROCD 2017), Lisbonne, Portugal, Oct 2017 [LillOA]
  15. M. Gehrke, T. Rongthong, G. Tourrel, D. Gnansia, P. Oliveira, J.-F. willart, L. Paccou, Y. Guinet, A. Hedoux, C. Vincent, F. Siepmann, J. Siepmann, Homogeneity, drug release and swelling of dexamethasone loaded cochlear implants, 11th world meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical technology, Granada, Espagne, Mar 2018 [LillOA]
  16. M.-J. Garcia Fernandez, N. Tabary, J.-F. willart, F. Chai, N. Blanchemain, M.-P. Leterme Flament, B. Martel, New pharmaceutical excipient based on polymers of cyclodextrins, 18ème Journées de la société française des cyclodextrines, Lens, France, Nov 2017 [LillOA]
  17. F. Affouard, J.-F. willart, F. Ngono Mebenga, G.J. Cuello, M. Jimenez-Ruiz, Structural investigation of amorphous lactulose by neutron diffraction experiment, Analysis of Diffraction Data in Real Space (ADD2016), Grenoble, France, Mar 2016 [LillOA]
  18. M.-J. Garcia Fernandez, N. Blanchemain, N. Tabary, J.-F. willart, M.-P. Leterme Flament, B. Martel, New pharmaceutical excipient based on polymers of cyclodextrins, Euro CD 2015 - 4th European conference on cyclodextrins, Lille, France, Oct 2015 [LillOA]
  19. J. Fahier, S. MUSCHERT, G. Byrne, J.-F. willart, F. Siepmann, J. Siepmann, Importance of Osmotic Effects for the Control of Drug Release from Kollicoat SR Coated Pellets, 42nd Annual Meeting & Exposition of the Controlled Release Society, Edinburgh, Royaume-Uni, Jun 2015 [LillOA]
  20. M. Gehrke, J. Sircoglou, D. Gnansia, G. Tourrel, J.-F. willart, F. Danede, F. Siepmann, J. Siepmann, Characterization of Ear Cubes for local controlled dexamethasone delivery to the inner ear, 4th Congress on Innovation in Drug Delivery : Site-Specific Drug Delivery, Antibes-Juan-les-pins, France, Sep 2016 [LillOA]
  21. A.M. Salah, J.-F. willart, Manipulation de l'état physique du tréhalose vitreux par activation mécanique, JCAT 45 - Journées de Calorimétrie et d'Analyse Thermique, Rouen, France, May 2014 [LillOA]
  22. E. Marcato, O. Cantin, F. Siepmann, F. Danede, J.-F. willart, J. Siepmann, y. karrout, How can peo hot melt extrudates control metoprolol release in vitro?, 2nd European Conference on Pharmaceutics: Novel dosage forms & innovative technologies, Kraków, Pologne, Apr 2017 [LillOA]
  23. A.-K. Vynckier, H. Lin, J. Zeitler, J.-F. willart, E. Bongaers, J. Voorspoels, Y. Gonnissen, J. Remon, C. Vervaet, Calendering as a direct shaping tool for the continuous production of fixed-dose combination products via co-extrusion, 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Lisbonne, Portugal, Mar 2014 [LillOA]
  24. E. Gue, S. MUSCHERT, J.-F. willart, F. Danede, E. Delcourt Debruyne, M. Descamps, J. Siepmann, Accelerated Ketoprofen Release from Spray-Dried Polymeric Particles, 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Lisbonne, Portugal, Mar 2014 [LillOA]
  25. E. Gue, J.-F. willart, S. MUSCHERT, F. Danede, M. Descamps, E. Delcourt Debruyne, J. Siepmann, Eudragit® E-Based Matrices for Accelerated Ketoprofen Release in Acidic Media, AMPTECH 2014 (Advanced Materials and Pharmaceutical TEChnologies), Villeneuve d'Ascq, France, Jul 2014 [LillOA]
  26. E. Gue, S. MUSCHERT, J.-F. willart, F. Danede, E. Delcourt Debruyne, M. Descamps, J. Siepmann, Accelerated Fenofibrate Release from Spray-Dried Microparticles Based on Polymer Blends, 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Lisbonne, Portugal, Mar 2014 [LillOA]
  27. E. Gue, J.-F. willart, S. MUSCHERT, F. Danede, M. Descamps, E. Delcourt Debruyne, J. Siepmann, Eudragit® E-Based Matrices for Accelerated Ketoprofen Release in Acidic Media, 3rd Conference on Innovation in Drug Delivery: Advances in Local Drug Delivery, Pisa, Italie, Sep 2013 [LillOA]
  28. E. Gue, S. MUSCHERT, J.-F. willart, F. Danede, E. Delcourt Debruyne, M. Descamps, J. Siepmann, The Ketoprofen Hot-Melt Extrudates with Accelerated Drug Release in 0.1 N HCl, APPS 2013 American Association of Pharmaceutical Scientists, San Antonio, Etats-Unis d'Amérique, Nov 2013 [LillOA]
  29. E. Bres, F. Houdvellier, J.-F. willart, A. Mahieu, M. Descamps, Analyse de matériaux thérapeutiques contraints par LACDIF, Symposium « les nanoparticules en biologie et pour les matériaux ». Société française de microscopie, Strasbourg, France, Sep 2011 [LillOA]
  30. P. Delcroix, L. Paccou, Y. Guinet, J.-F. willart, F. Danede, B. Hanoune, Propriétés physicochimiques de solutions aqueuses de formaldéhyde, Journées Interdisciplinaires de la Qualité de l'Air, Villeneuve d'Ascq, France, Feb 2010 [LillOA]
  31. Y. Jallouli, J.-F. willart, M. Descamps, J. Siepmann, Dissolution kinetics of a poorly soluble drug co-formulated with hydrophilic polymers: impact of the type of preparation technique, 7th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, La Valette, Malte, Mar 2010 [LillOA]